Periodontitis
Conditions
Interventions
Experimental group:FGG combined with periodontal tissue regeneration two-stage method
Control group:periodontal tissue regeneration
Sponsors
Shanghai Stomatological Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Diagnosed with stage III or IV Grade C periodontitis according to the 2017 consensus classification of periodontal disease and peri-implant diseases and conditions; 3. According to imaging examination, there was at least one subosseous defect with depth >=3mm on both sides; 4. The keratinized gingival width of the defect site is less than 2mm; 5. Probing depth (PD) in subbone defect sites was >=5mm and Bleeding Index (BI) was >=2. 6. Live pulp or complete root canal treatment; 7. Good compliance, good oral hygiene habits; 8. Access to informed consent.
Exclusion criteria
Exclusion criteria: 1. Smoking; 2. Pregnant or lactating patients; 3. Patients suffering from tumor, diabetes, cardiovascular disease and other systemic diseases; 4. Any situation that is not suitable for periodontal surgery; 5. The affected tooth has III degrees root bifurcation lesion or III degrees loosening; 6. Periodontal operation was performed on the affected tooth; 7. The investigator considered that other reasons were not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of clinical attachment loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| change of clinical attachment loss;change of probing depth;changes in intrabony defect depth and vertical bone loss;change of keratinized tissue width; | — |
Countries
China
Contacts
Public ContactChen Meihua
Shanghai Stomatological Hospital
Outcome results
None listed