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PTi-guided Remifentanil Combined with Propofol Target-Controlled Infusion General Anesthesia: A comparison with medication under standard monitoring

PTi-guided Remifentanil Combined with Propofol Target-Controlled Infusion General Anesthesia: A comparison with medication under standard monitoring

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063170
Enrollment
Unknown
Registered
2022-09-01
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; 2. ASA grade I-III; 3. 20<=BMI < 25kg/m^2; 4. The estimated operation time is 2-6h; 5. Informed consent can be signed.

Exclusion criteria

Exclusion criteria: 1. Received any form of local anesthesia during perioperative period; 2. Patients with expected difficult airway; 3. Combined with central or peripheral nervous system diseases; 4. Baseline SBP 140 mmHg, baseline heart rate 90 bpm; 5. Patients with arrhythmia and pacemaker application; 6. Combined liver and kidney insufficiency; 7. Have used opioids within 30 days; 8. Drug abuse; 9. Suffers from mental illness or is unable to work together; 10. Those who participated in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Rifentanil dosage;Opioid dosage 48 hours postoperatively;

Secondary

MeasureTime frame
Numeric rating scale score for pain;Ramsay score;Type, time and dosage of vasoactive drugs;Postoperative recovery room stay time;Bispectral index (BIS) value of EEG;Analgesic index(PTi);Blood pressure;Heart rate;The time between the end of the operation and the time of extubation;Intraoperative hypertension/hypotension events;TacIntraoperative hycardia/bradycardia events;Intraoperative awareness;

Countries

China

Contacts

Public ContactYang Jianjun
Jianjunyang1971@163.com+86 13783537619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026