Relationship between cognitive reserve and longitudinal changes in cognitive function in patients with preclinical dementia (subjective cognitive decline, mild cognitive impairment): a cohort study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200063160

Enrollment

Unknown

Registered

2022-09-01

Start date

2022-09-05

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subjective cognitive decline (SCD)

Interventions

Exposure group:NA

Non-exposed group:NA

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=50 years; 2. Meet the aforementioned diagnostic criteria for SCD and MCI; 3. Normal audiovisual ability, no communication barriers; 4. Life in the city, no relocation plan in the coming year; 5. Voluntarily participate in this study and agree to accept regular review and follow-up.

Exclusion criteria

Exclusion criteria: 1. Severe head injury or intracranial lesions, or suffering from other neurological diseases (such as Parkinson's disease, stroke, multiple sclerosis, etc.); 2. People with severe mental disorders; 3. The first round of follow-up was lost and key prediction information was lost.

Design outcomes

Primary

Measure	Time frame
Cognitive Reserve Scale;Montreal Cognitive Assessment (MoCA);Body Mass Index(BMI);Head MRI;	—

Countries

China

Contacts

Public ContactChen Li

School of Nursing, Jilin University

chenl@jlu.edu.cn+86 431 85619366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026