Randomized controlled trial of spiral oxygen therapy exhalation device to improve the treatment effect of patients with severe pneumonia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200063145

Enrollment

Unknown

Registered

2022-08-31

Start date

2022-09-01

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe pneumonia

Interventions

intervention group:New artificial airway high flow humidifying oxygen therapy device (NTHF) high flow humidifying oxygen therapy

control group:Respiratory humidification therapy apparatus

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient aged >=18 years, meeting the diagnostic criteria for severe pneumonia; 2. Have an artificial airway ready or have been removed from the ventilator; 3. Need to receive oxygen therapy > 24h; 4. Expected retention days of tracheal catheter >=7 days; 5. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with single lung ventilation; 2. Pregnancy and end-stage cancer patients; 3. Airway bleeding; 4. History of airway injury, lung injury and lung surgery; 5. Hypothermia (< 35?), limited fluid insufficiency.

Design outcomes

Primary

Measure	Time frame
flow rate near the patientflow rate;	—

Secondary

Measure	Time frame
airway humidification effect;blood gas analysis;oxygenation Index;mechanical ventilation time;	—

Countries

China

Contacts

Public ContactYang Mei

Shenzhen Second People's Hospital

Yangmei3056@163.com+86 13509682339

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026