Lumbar spinal stenosis
Conditions
Interventions
High-dose group:Tranexamic acid was injected intravenously 50mg/kg before surgery
Low-dose group:Tranexamic acid was injected intravenously 20mg/kg before surgery
Control group:None
Sponsors
Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Tibetan patients aged 18 to 80 years in Tibet; 2. Posterior spinal decompression and fusion surgery for thoracic and/or lumbar degenerative diseases; 3. Normal coagulation function before operation; 4. Get informed consent.
Exclusion criteria
Exclusion criteria: 1. History of venous thromboembolism, pulmonary embolism, cerebral infarction and coronary heart disease; 2. Blood coagulation disorder; 3. Anticoagulant drugs are being used; 4. Clearly allergic to tranexamic acid; 5. Severe liver and kidney insufficiency; 6. Patients at high risk for thrombosis, including atrial fibrillation, pacemaker and stent implantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasound of lower extremity veins; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fibrinogen degradation product (FDP);D-dimer; | — |
Countries
China
Contacts
Public ContactZhang Bin
Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region
Outcome results
None listed