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Effects of electrical stimulation of the median nerve on the excitability of the cerebral cortex and its mechanism

Effects of electrical stimulation of the median nerve on the excitability of the cerebral cortex and its mechanism

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063093
Enrollment
Unknown
Registered
2022-08-30
Start date
2022-08-31
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cortico-motor plasticity

Interventions

Group 1 :Median nerve stimulate

Sponsors

The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Male or female; 2. Agree to receive median nerve stimulation (MNS) intervention; 3. Agree and have the ability to learn the procedure, including an adequate level of cognitive understanding; 4. Age 18-50 years old; 5. Junior high school and above; 6. Right-handed.

Exclusion criteria

Exclusion criteria: 1. Childhood traumatic experience (physical, psychological, sexual abuse); 2. Meet the current criteria for major depression, bipolar disorder, schizophrenia, any mental illness (including drug-induced mental illness) and current drug-induced mood disorder; 3. Suffering from delusions, dementia, amnesia, obsessive-compulsive disorder, post-traumatic stress disorder, anxiety disorder, any personality disorder, cognitive disorder or dissociative disorder; 4. Serious physical diseases, history of heart disease, cardiac pacemaker or implanted drug pump, etc.; 5. Have serious negative concepts and behaviors; 6. Pregnant and lactating women; 7. Metal implants in the brain, cochlear implants, increased intracranial pressure, traumatic brain injury, skull insufficiency, encephalitis, brain tumors; 8. Have any neurological diseases, epilepsy, Parkinson's, stroke, etc., have a family history of epilepsy, and use anticonvulsant drugs; 9. Suffering from cardiovascular and cerebrovascular diseases such as hypertension; 10. Cerebral calcification and cerebral microbleeds exist; 11. Obesity, body mass index > 35 kg/m2; 12. Having sleep deprivation.

Design outcomes

Secondary

MeasureTime frame
Double pulse transcranial magnetic evaluation of motor cortex;

Primary

MeasureTime frame
peak motor evoked potential;recruitment curve;

Countries

China

Contacts

Public ContactYing Shen

The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University

shenying_1981@hotmail.com+86 13913913930

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026