cortico-motor plasticity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female; 2. Agree to receive median nerve stimulation (MNS) intervention; 3. Agree and have the ability to learn the procedure, including an adequate level of cognitive understanding; 4. Age 18-50 years old; 5. Junior high school and above; 6. Right-handed.
Exclusion criteria
Exclusion criteria: 1. Childhood traumatic experience (physical, psychological, sexual abuse); 2. Meet the current criteria for major depression, bipolar disorder, schizophrenia, any mental illness (including drug-induced mental illness) and current drug-induced mood disorder; 3. Suffering from delusions, dementia, amnesia, obsessive-compulsive disorder, post-traumatic stress disorder, anxiety disorder, any personality disorder, cognitive disorder or dissociative disorder; 4. Serious physical diseases, history of heart disease, cardiac pacemaker or implanted drug pump, etc.; 5. Have serious negative concepts and behaviors; 6. Pregnant and lactating women; 7. Metal implants in the brain, cochlear implants, increased intracranial pressure, traumatic brain injury, skull insufficiency, encephalitis, brain tumors; 8. Have any neurological diseases, epilepsy, Parkinson's, stroke, etc., have a family history of epilepsy, and use anticonvulsant drugs; 9. Suffering from cardiovascular and cerebrovascular diseases such as hypertension; 10. Cerebral calcification and cerebral microbleeds exist; 11. Obesity, body mass index > 35 kg/m2; 12. Having sleep deprivation.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Double pulse transcranial magnetic evaluation of motor cortex; | — |
Primary
| Measure | Time frame |
|---|---|
| peak motor evoked potential;recruitment curve; | — |
Countries
China
Contacts
The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University