Ocular rosacea
Conditions
Interventions
Experimental group:erythromycin eye ointment in combination with Intense pulsed light
Control group:erythromycin eye ointment in combination with sham Intense pulsed light
Sponsors
Beijing University First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Over 18 years old; 2. Definitely diagnosed as rosacea; 3. Diagnosis of meibomian gland dysfunction of grade 2 or above in both eyes, and the difference in grade of meibomian gland dysfunction in both eyes is <= 1 grade; 4. Volunteer to join this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot see a doctor for a long time; 2. Other eye surgery or eye injury history within 6 months before the study; 3. Laser treatment around the eyes or face in the past 6 months; 4. Has a history of eye medication other than artificial tears and erythromycin eye ointment in the past 1 month; 5. IPL treatment contraindications (such as: previous history of facial herpes virus infection, pregnancy, epilepsy, etc.); 6. There are systemic diseases, including Sjogren's syndrome, graft-versus-host disease, Stevens-Johnson syndrome, and pemphigoid; 7. History of eye acid or alkali burns; 8. Wear contact lenses 48 hours before the test and during the study; 9. Implants under the treatment area; 10. There are tattoos in the treatment area; 11. Lactating or pregnant women; 12. Taking photosensitive drugs, such as isotretinoin, tetracycline or St. John's Wort; 13. Patients with eyelid abnormalities (such as entropion, ectropion, tumor, edema, blepharospasm, insufficiency of eyelid closure, trichiasis, ptosis, eyelid relaxation, etc.); 14. Glaucoma patients; 15. The researchers think that they are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear break-up time; | — |
Countries
China
Contacts
Public ContactYan Xiaoming
Beijing University First Hospital
Outcome results
None listed