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Effectiveness and safety of Yifei Sanjie Granule in people with pulmonary solid nodules: a prospective cohort study

Effectiveness and safety of Yifei Sanjie Granule in people with pulmonary solid nodules: a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200063078
Enrollment
Unknown
Registered
2022-08-30
Start date
2022-08-31
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary solid nodules

Interventions

Group 1 :
Group 2:

Sponsors

The Third Affiliated Hospital of Henan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with solid pulmonary nodules of medium volume (50-500 mm3, equivalent to 4.6-9.8 mm in diameter) diagnosed by chest spiral CT thin-layer scan and artificial intelligence pulmonary nodules; 2. 18 <= age <= 80 years old; 3. Good communication and understanding skills; 4. Volunteer and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with systemic and/or respiratory symptoms such as fever, cough, sputum, hemoptysis, and dyspnea; 2. Patients with malignant signs of nodules (vacuoles, eccentric cavities, bronchial signs, burrs, lobes, vascular bundles, pleural traction, etc.), who are recommended to undergo PETCT, biopsy or surgery after multidisciplinary consultation; 3. Consider patients with benign diseases such as intrapulmonary lymph nodes, hamartomas, and sclerosing alveolar cell tumors, or patients with obvious benign features such as calcification of nodules; 4. Consider patients with metastatic pulmonary nodules; 5. Patients with organ failure caused by various systemic diseases; 6. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
The regression rate of nodule;The volume doubling time;

Secondary

MeasureTime frame
The growth rate of nodule;The largest diameter in the transaxial plane of the nodule;Nodule volume;Mean CT value in the transaxial plane of the nodule;

Countries

China

Contacts

Public ContactLi Jiansheng

The Third Affiliated Hospital of Henan University of Chinese Medicine

li_js8@163.com+86 371 66248624

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026