Skip to content

Evaluation of the antiplatelet effect of cilostazol by plasma concentration and cAMP content in plasma and platelets

Evaluation of the antiplatelet effect of cilostazol by plasma concentration and cAMP content in plasma and platelets

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063063
Enrollment
Unknown
Registered
2022-08-29
Start date
2022-08-31
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Group 1 :Aspirin 100 mg,qd combined with cilostazol 100 mg,bid

Sponsors

Affiliated Drum Tower Hospital of Nanjing University Medical School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Patients with cerebral infarction who are taking dual-antibody therapy, aspirin 100 mg, qd combined with cilostazol 100 mg, bid; 3. Able to cooperate with follow-up visits.

Exclusion criteria

Exclusion criteria: 1. Simultaneous use of other anticoagulant, antiplatelet, defibrinating or other drugs that affect blood coagulation; 2. The survival period of the patient is < 1 year due to various reasons; 3. Contraindications to antithrombotic drug therapy, or related drug allergies; 4. Patients with severe heart, liver and kidney insufficiency; 5. Participate in other clinical research within 3 months; 6. Serum HIV positive; 7. Patients with severe mental disorders, cognitive dysfunction, or patients who cannot understand and sign the informed consent form; 8. Coagulation dysfunction, active bleeding or bleeding tendency; 9. The double antibody has been taken continuously for less than 3 months since the enrollment.

Design outcomes

Primary

MeasureTime frame
Plasma drug concentration;Plasma cAMP concentration;cAMP concentration in platelets;Clinical symptoms;Modified Rankin Scale score;National Institutes of Health Stroke Scale score;

Countries

China

Contacts

Public ContactTengfei Shao

Affiliated Drum Tower Hospital of Nanjing University Medical School

shaotf@126.com+86 18913898337

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026