retroperitoneal laparoscopic surgery
Conditions
Interventions
Group 1 :Patients are assigned for opioid-based anaesthesia with propofol, sufentanil, remifentanil and sevoflurane.
Group 2:Patients are assigned for opioid-free anaesthesia with propofol, dexmedetomidine, esketamine and sevoflurane.
Sponsors
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-70 years old; 2. ASA I-III level; 3. Patients undergoing elective retroperitoneal laparoscopic surgery.
Exclusion criteria
Exclusion criteria: 1. Contraindications to regional nerve blocks, including skin infection or bleeding disorders at the block site; 2. Those who are allergic to any drugs used in this test; 3. Patients with severe cardiovascular and cerebrovascular diseases, respiratory diseases and abnormal liver and kidney function before operation; 4. History of chronic pain, long-term use of opioids, hormones or non-steroidal drugs; 5. BMI >= 30 kg/m2; 6. Unable to communicate normally: hearing impairment, language comprehension impairment, mental illness, etc.; 7. Has participated in other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality-40; | — |
Countries
China
Contacts
Public ContactZhao Linlin
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed