Effect of anisodamine on fetal oxygen partial pressure and Apgar score in patients with late-onset preeclampsia during perioperative period

Effect of anisodamine on fetal oxygen partial pressure and Apgar score in patients with LO-PE during perioperative period

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200063049

Enrollment

Unknown

Registered

2022-08-29

Start date

2022-08-15

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Late-onset preeclampsia

Interventions

Experimental group:Anisodamine was administered intravenously

Conrol group:Normal saline was given intravenously

Eligibility

Sex/Gender

Female

Age

21 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Women who meet the diagnostic criteria of "Obstetrics and Gynecology (Seventh Edition)" and are first diagnosed as late-onset preeclampsia with hypertensive disorders during pregnancy; 2. ASA II-III grade, single pregnancy, no contraindication of neuraxial anesthesia.

Exclusion criteria

Exclusion criteria: 1. Previous history of hypertension; 2. Fetal distress in uterus; 3. Combined with other pregnancy complications; 4. Combined with serious organic diseases of heart, brain, kidney and other important organs; 5. With contraindications such as increased intracranial pressure, glaucoma, and pyloric obstruction; 6. Abnormal coagulation function.

Design outcomes

Primary

Measure	Time frame
Fetal blood oxygen partial pressure;Apgar score;	—

Countries

China

Contacts

Public ContactXu Ying

The Third Affiliated Hospital of Zunyi Medical University

337368230@qq.com+86 15329329737

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026