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Mechanism of transcutaneous electrical acupoint stimulation on improving POCD and CCL-2

Mechanism of transcutaneous electrical acupoint stimulation on improving POCD and CCL-2

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063030
Enrollment
Unknown
Registered
2022-08-28
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar screw internal fixation + spinal decompression and fusion

Interventions

Group A:Transcutaneous electrical acupoint stimulation, intervention for 3 days
Group B:Transcutaneous electrical acupoint stimulation, intervened for 7 days
Group C:Comfort type Han acupoint nerve stimulator

Sponsors

The First Affiliated Hospital of Gannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 60-80 years old; 2. ASA I-III level; 3. Able to speak Mandarin and communicate, with education level > 9 years; 3. Heart, lung, liver, and kidney functions have no obvious abnormalities; 4. The operation time is less than 3 hours.

Exclusion criteria

Exclusion criteria: 1. Patients with preoperative cognitive impairment, patients with a history of dementia and delirium; 2. Patients with severe depression, schizophrenia and other mental and nervous system diseases or who have taken antipsychotic or antidepressant drugs; 3. Use of anti-inflammatory drugs, glucocorticoids or other hormonal drugs, alcohol or drug dependence; 4. Severe heart, lung, liver and kidney dysfunction; 5. Hearing or visual impairment cannot complete the test score; 6. The skin around the target acupuncture point has ulceration and infection; 7. Mini-Mental State Examination (MMSE) 800 ml, hospitalized for 3 months or more.

Design outcomes

Primary

MeasureTime frame
Score on the Mini-Mental Rating Scale;

Secondary

MeasureTime frame
Interleukin-6;Tumor necrosis factor ?;Neuron-specific enolase;S100ß;Chemokine ligand 2;

Countries

China

Contacts

Public ContactWang Lifeng

The First Affiliated Hospital of Gannan Medical College

wwwanglifeng@126.com+86 13576715202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026