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Effects of Perioperative Transfusion Trigger Score guided blood transfusion strategy on prognosis and cerebral oxygen metabolism and other mechanisms in elderly surgical patients

Effects of Perioperative Transfusion Trigger Score guided blood transfusion strategy on prognosis and cerebral oxygen metabolism and other mechanisms in elderly surgical patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062976
Enrollment
Unknown
Registered
2022-08-25
Start date
2022-08-25
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of Perioperative Transfusion Trigger Score on prognosis in elderly surgical patients

Interventions

Sponsors

The Second Nanning People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Surgical patients, aged = 60 years; (2) American Society of anesthesiologists (ASA) class I-III; (3) The perioperative Hb was 60-100g / L.

Exclusion criteria

Exclusion criteria: (1) Serious hematological disease . (2) Hemoglobin oxygen carrying capacity. (3) Must undergo hypervolemic hemodilution. (4) Heart and blood vessel surgery, brain surgery, burn surgery; (5) History of acute stroke or mental illness. (6) Uncontrolled severe hypertension or hypotension (systolic blood pressure = 160 mmHg, diastolic blood pressure = 100 mmHg, systolic blood pressure = 90 mmHg, diastolic blood pressure = 60 mmHg, which can meet any one), severe arrhythmia and unstable angina pectoris. (7) Long-term bed rest before admission (bed rest time = 1 month). (8) Has participated in other drug clinical trials as a subject in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Transfusion rate;Volume of total blood transfusion;Incidence of postoperative delirium;mortality;Incidence of serious postoperative complications;

Secondary

MeasureTime frame
Postoperative hemoglobin value;Arterial blood lactic acid;Oxygen saturation of internal jugular vein;CD3+, CD4+, CD4+/CD8+ratio;IL-1ß, IL-6, IL-8, CRP, TNF-a;cortisol level;

Countries

China

Contacts

Public ContactHuang Yanjuan
huangyanjuan66@163.com+8613878825731

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026