Effects of Perioperative Transfusion Trigger Score on prognosis in elderly surgical patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Surgical patients, aged = 60 years; (2) American Society of anesthesiologists (ASA) class I-III; (3) The perioperative Hb was 60-100g / L.
Exclusion criteria
Exclusion criteria: (1) Serious hematological disease . (2) Hemoglobin oxygen carrying capacity. (3) Must undergo hypervolemic hemodilution. (4) Heart and blood vessel surgery, brain surgery, burn surgery; (5) History of acute stroke or mental illness. (6) Uncontrolled severe hypertension or hypotension (systolic blood pressure = 160 mmHg, diastolic blood pressure = 100 mmHg, systolic blood pressure = 90 mmHg, diastolic blood pressure = 60 mmHg, which can meet any one), severe arrhythmia and unstable angina pectoris. (7) Long-term bed rest before admission (bed rest time = 1 month). (8) Has participated in other drug clinical trials as a subject in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transfusion rate;Volume of total blood transfusion;Incidence of postoperative delirium;mortality;Incidence of serious postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hemoglobin value;Arterial blood lactic acid;Oxygen saturation of internal jugular vein;CD3+, CD4+, CD4+/CD8+ratio;IL-1ß, IL-6, IL-8, CRP, TNF-a;cortisol level; | — |
Countries
China