Cardiovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Proposed cardiac surgery 2. Aged >18 years 3. Sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Emergency operation patients; 2. Mechanical ventilation time >1 hour within 2 weeks before surgery; 3. COPD requiring oxygen therapy or continuous positive pressure ventilation (CPAP) before surgery, history of severe or uncontrolled bronchial asthma or history of severe restrictive lung disease; 4. Preoperative diagnosis of acute respiratory failure (including pneumonia, acute lung injury or acute respiratory distress syndrome); 5. Involvement in cardiothoracic surgery or history of cardiothoracic surgery; 6, preoperative hemodynamic instability or congestive heart failure (NYHA III-IV or GOLD III-IV) or persistent ventricular arrhythmias; 7, preoperative combined with moderate to severe hepatic and renal insufficiency or renal replacement therapy (CRRT), liver function Child Pugh B or C; 8. Pregnancy or lactation; 9. Death during surgery or expected survival time after surgery <72 hours; 10. Patients deemed unsuitable for the study group by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day mortality;Mechanical ventilation time>48H;The lung injury score (Murray score); | — |
Countries
China