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Effect of bacterial transplantation on Intestinal Flora imbalance in uremic hemodialysis patients with constipation

Effect of bacterial transplantation on Intestinal Flora imbalance in uremic hemodialysis patients with constipation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062958
Enrollment
Unknown
Registered
2022-08-25
Start date
2022-08-26
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease

Interventions

Bacterial transplantation group:Bacterial transplantation

Sponsors

Jinan Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) age 18-60 Years Without Gender Limitation; (2) maintenance hemodialysis patients (=3 months) with 2-3 dialysis sessions per week; (3) meeting the diagnostic criteria for intestinal dysfunction; (4) consenting to the use of fecal bacteria transplantation (FMT) for the treatment of intestinal dysfunction; Sign the informed consent form voluntarily.

Exclusion criteria

Exclusion criteria: (1) allergic or intolerant to probiotics; (2) use of antibiotics or Antifungal drugs during the interphase of treatment; oral probiotics (capsule or powder, etc.)15 days before treatment; (4) patients with advanced cancer; (5) patients with colonic obstructive disease; (6) severe cardiac dysfunction (Nyha class 3 or above) and poor control of hypertension (systolic blood pressure =180 mm hg or diastolic blood pressure =100 mm Hg) ; (7) life expectancy of less than 12 months; (8) has participated in or is currently participating in other clinical trials in the last 3 months (9) patients with stomach and peptic Ulcer Ulcerative Colitis; (10) conditions that researchers believe may affect compliance or affect the outcome of a trial.

Design outcomes

Primary

MeasureTime frame
Detection of Faecal Flora genes;

Secondary

MeasureTime frame
FECAL metabonomics;

Countries

China

Contacts

Public ContactGuan WenYu
850285685@qq.com18953117225

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026