Clinical study of EEG predicting recurrence of infantile spasms

EEG BASED score is a predictive model for long-term prognosis after ACTH treatment in infantile spasms

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200062952

Enrollment

Unknown

Registered

2022-08-25

Start date

2022-09-01

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infantile spasms

Interventions

Observation groups:None

Eligibility

Sex/Gender

All

Age

No minimum to 2 Years

Inclusion criteria

Inclusion criteria: Definitively diagnosed children with IS; Hospitalization in our hospital and completion of 14 days of ACTH treatment; Complete cessation of spastic episodes at the end of ACTH treatment; 4. Complete an EEG review 2-3 days before the completion of ACTH infusion.

Exclusion criteria

Exclusion criteria: Those who adjust antiepileptic drugs during ACTH therapy; Those who adjust antiepileptic drugs after acth therapy is completed or before relapse; Frequency of spastic episodes < 1 time / day; Clinical or re-examination of EEG after ACTH treatment shows that there are still spastic occurrences; EEG data is missing or there is a significant pseudo-difference in the background; Lack of clinical data; Follow-up < 1 year; Recurrence has a clear precipitating cause (e.g., severe infection or trauma).

Design outcomes

Primary

Measure	Time frame
BASED score;electroencephalogram;	—

Countries

China

Contacts

Public ContactGuang Yang

yangg301@sina.com13810692267

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026