Barrett's esophagus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects who can participate in this study must meet all the following criteria: 1. Age 18-75 years old, gender unlimited 2. Patients diagnosed as BE endoscopically or histopathologically 3. Voluntarily participate in this study and sign the informed consent form
Exclusion criteria
Exclusion criteria: Subjects should not participate in the study if in any of the following conditions 1. Previously diagnosed with esophageal cancer 2. Those who have previously received BE endoscopic treatment or BE surgery 3. Serious heart disease or serious respiratory disease 4. Suspected of shock, peritonitis, esophageal or gastrointestinal perforation 5. Acute stage of corrosive esophageal injury 6. Acute severe throat disease 7. Severe esophageal varices 8. Patients with obvious thoracic abdominal aortic aneurysm 9. Patients with acute cerebrovascular disease 10. Those who are taking or have a history of taking anticoagulant drugs and severe anemia (blood routine examination hemoglobin < 50g / L) 11. Patients who are allergic to fluorescein sodium 12. Patients who cannot tolerate upper gastrointestinal endoscopy under general intravenous anesthesia 13. Pregnant or lactating women 14. Patients with mental illness cannot cooperate with the examination 15. Patients who have participated in other clinical trials within 30 days 16. Other patients who researchers think are not suitable to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coincidence rate between pathological results of targeted biopsy guided by pCLE and pathological results of random biopsy. ; | — |
Countries
China