gastric cancer
Conditions
Interventions
experimental group:lymph node dissection guided by 3D fluorescent laparoscopy and ICG NIR imaging
control group:D2 lymph node dissection with Common visible light source 3D laparoscopy
Sponsors
Peking University Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged between 18 and 80 Primary gastric adenocarcinoma confirmed histologically (papillary, tubular, mucinous, signed-ring cell, poorly differentiated) Clinical stages were cT1-4a, Nany, M0 according to the 8th edition of AJCC staging With or without neoadjuvant chemotherapy ECOG score 0 or 1 A KPS score of 70 or higher Sign written informed consent
Exclusion criteria
Exclusion criteria: Pregnant or breastfeeding women Severe mental illness /serious underlying illness or condition: Such as clinically severe (activities) heart disease, serious, uncontrolled medical disease and infection, serious uncontrolled digestive system disorders, severe electrolyte disorder, active disseminated intravascular coagulation; major organ failure, such as decompensated heart, lung, liver, kidney failure, peripheral neuropathy symptoms etc., in which situation that D2 radical gastrectomy was not tolerated. History of upper abdominal surgery (except for laparoscopic cholecystectomy) Previous gastric surgery (excluding ESD and EMR) Preoperative imaging showed tumors larger than 5cm in length, leather stomach or presence of Bulky N lymph nodes (more than 3cm) Other malignancies within 5 years Unstable angina attack or myocardial infarction within 6 months Emergency surgery (due to bleeding, obstruction, perforation, etc.)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Noncompliance rate of lymph nodes;Lymph node metastasis rate;Postoperative complications and perioperative death;Postoperative recovery;operation time;intraoperative blood loss;blood amylase after operation;Postoperative changes in hemoglobin;Postoperative leucocyte changes;Postoperative CRP changes;subjective evaluation of laparoscopic equipment; | — |
Primary
| Measure | Time frame |
|---|---|
| total retrieved Lymph Nodes in D2 region; | — |
Countries
China
Contacts
Public ContactLi Ziyu
Peking University Cancer Hospital
Outcome results
None listed