Thyroid Nodules
Conditions
Interventions
CEUS-FNA:contrast enhanced ultrasound guided
US-FNA:conventional ultrasound guided
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Thyroid nodule confirmed by ultrasound; 3. Nodule meets the FNA criteria recommended by the C-TIRADS guidelines; 4. Nodule meets one of the following criteria for high risk of inadequacy: (1) Nodule with high cystic component: cystic (solid portion = 3 mm marcocalcification, visible solid protion = 95%) or predominantly solid (50% <= solid portion < 95%), hypoechoic or very-hypoechoic, avascular, hypoechoic halo, with or without macrocalcification; (4) Suspicious PTC with severe fibrosis: very-hypoechoic, posterior echogenic attenuation or acoustic shadowing, avascular; 5. The informed consent form has been signed.
Exclusion criteria
Exclusion criteria: 1. Allergic to lidocaine or SonoVue; 2. Refusal to CEUS; 3. Severe cardiac and pulmonary abnormalities; 4. Severe coagulation abnormalities; 5. Pregnancy; 6. Active infected lesions on the skin of the neck; 7. Physical and psychological barriers to cooperation with FNA or CEUS: psychiatric disorders, excessive obesity, post-tracheotomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FNA specimen inadequate rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| immediate complication rate;operative time; | — |
Countries
China
Contacts
Public ContactTinghui Yin
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed