mild hyperlipidemia
Conditions
Interventions
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. No limitation of ethnic groups; 3. Both sexes; 4. Patients with mild hyperlipidemia: (1) hypertriglyceridemia (1.7 mmol/L <= TG < 2.3 mmol/L), (2) hypercholesterolemia (5.2 mmol/L <= TC < 6.2 mmol/L or 3.4 mmol/L <= LDL-C < 4.1 mmol/L, (3) mixed hyperlipidemia (1.7 mmol/L <= TG < 2.3 mmol/L and 5.2 mmol/L <= TC < 6.2 mmol/L, or 1.7 mmol/L<= TG < 2.3 mmol/L and 3.4 mmol/L<= LDL-C < 4.1 mmol/L,or 1.7 mmol/L <= TG < 2.3 mmol/L and 5.2 mmol/L <= TC < 6.2 mmol/L and 3.4 mmol/L<= LDL-C < 4.1 mmol/L); 5. Have communication and cognitive ability, can adhere to long-term medication; 6. Volunteer to join the experiment.
Exclusion criteria
Exclusion criteria: 1. Those who are receiving lipid-lowering drugs; 2. Hyperlipidemia caused by secondary causes, such as nephrotic syndrome, liver disease, hypothyroidism, renal failure, etc.; 3. Patients with severe diabetes, hypertriglyceridemia, cerebrovascular diseases and other major diseases requiring immediate treatment, and patients with heart disease, immune system diseases, acute onset of chronic diseases, infectious diseases and malignant tumors; 4. Patients with severe primary diseases of liver, kidney and hematopoietic system or mental illness; 5. Pregnant or lactating women; 6. Allergic constitution and allergic to the test drugs; 7. Patients with a history of gallbladder surgery or gastrointestinal polyp surgery that affected the test results; 8. Participating in nutritional intervention studies; 9. Use antibiotics or take probiotics or other prebiotic preparations within 3 months of recruitment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood lipids;body composition;waistline;gut microbiota;serum lipid metabolites;bile acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic and renal function;fasting blood-glucose;fasting insulin;serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactXueyong Wang
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine
Outcome results
None listed