postoperative pulmonary complications
Conditions
Interventions
Group iPEEP (individual positive end-expiratory pressure):PEEP are titrated according to the optimal pulmonary static compliance (Cstat) method
Group fix PEEP:PEEP is set to a fixed 4 cmH2O
Sponsors
Beijing Friendship Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-85 years; 2. Patients scheduled for laparoscopic colorectal surgery undergoing general anesthesia and surgical times are predicted to >= 2 hours; 3. BMI is 18-30 kg/m2; 4. American Society of Anesthesiologists(ASA) physical status I-III; 5. NYHA grades I-II; 6. Moderate or high risk for postoperative pulmonary complications.(Assess Respiratory Risk in Surgical Patients in Catalonia, ARISCAT>= 26).
Exclusion criteria
Exclusion criteria: 1. Patients with severe chronic obstructive pulmonary disease (COPD, GOLD grades III–IV), or a history of severe or uncontrolled bronchial asthma; 2. Patients with conditions that may affect the compliance of the respiratory system such as thoracic deformity, pneumothorax, and massive pleural effusion; 3. Patients with severe liver and kidney dysfunction; 4. Patients with a forced expiratory volume in the first second/forced vital capacity; (FEV1/FVC) ratio < 70%; 5. Patients with a smoking history within 8 weeks before surgery; 6. Patients expected to return to ICU after surgery; 7. Patients who refuse to participate in the experiment by themselves or their families.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung ultrasound score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Pulmonary Complications;ventilation parameters;Anesthesia related parameters;30-day postoperative readmission rate;Quality of life assessment;Oxygenation Index;arterial blood gas; | — |
Countries
China
Contacts
Public ContactXiaofang Hao
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed