Invasive lung adenocarcinoma and its precancerous lesions
Conditions
Interventions
Gold Standard:Routine pathological diagnosis of pulmonary masses after operation.
molecule 
and 
proteomic 
differences.
Sponsors
Shenzhen Hospital of Peking University
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 25-75 years who were hospitalized in Shenzhen Hospital of Peking University from 2022 to 2025, underwent lobectomy or segmental lung resection, and were diagnosed with atypical adenomatous hyperplasia of the lung, carcinoma in situ, microinvasive adenocarcinoma of the lung and invasive adenocarcinoma of the lung by frozen section; 2. Were not treated with any radiotherapy or chemotherapy before operation, and had no other tumor history before operation; 3. The diagnosis was confirmed by routine paraffin section. After diagnosis by two or more physicians with senior titles of Pathology, an agreement was reached; 4. All patients signed the informed consent form and agreed to use the tissue for the study. The samples were fresh lung tissue sent to the pathology department, and the tissue or paraffin tissue required to be subjected to frozen section examination.
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In situ mass spectrometry scanning; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunohistochemistry;Targeted proteomics;qPCR;Transcriptome sequencing; | — |
Countries
China
Contacts
Public ContactLili Tao
Shenzhen Hospital of Peking University
Outcome results
None listed