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Esketamine combined with tramadol for patient controlled intravenous analgesia after cesarean section: a randomized control trial

Esketamine combined with tramadol for patient controlled intravenous analgesia after cesarean section: a randomized control trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062848
Enrollment
Unknown
Registered
2022-08-20
Start date
2022-08-20
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Control group:Postoperative analgesic pump formula of the control group is butorphanol tartrate 5 mg+tramadol hydrochloride 400mg, diluted to 100 mL with normal saline
Experimental group:The analgesic pump formula in the experimental group is esketamine hydrochloride 50 mg+tramadol hydrochloride 40 mg, diluted to 100 mL with normal saline

Sponsors

The People's Hospital of Pizhou
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged older than 18 years; 2. Those with American Society of Anesthesiologists class ?-?; 3. Those who will receive spinal anesthesia; 4. Those who will undergo elective or emergency cesarean section; 5. Those who will receive patient controlled intravenous analgesia (PCIA) .

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to or addicted to any drug in this study; 2. Those with pregnancy-induced hypertension, preeclampsia, eclampsia and other pregnancy complications or other underlying diseases; 3. Those who cannot accurately understand the NRS pain score and EPDS score; 4. Those who have been involved with other investigators before the start of the trial.

Design outcomes

Primary

MeasureTime frame
numerical rating scale (NRS) score;

Secondary

MeasureTime frame
Incidence of adverse reactions;

Countries

China

Contacts

Public ContactGuo Yihui

The People's Hospital of Pizhou

623099002@qq.com+86 15380117683

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026