Knee Osteoarthritis
Conditions
Interventions
one:ultrasound-guided suprapatellar bursal injection of Hypertonic glucose
two:injected 5% dextrose into the sensory nerves around the knee jointr under ultrasound guidance
three:Injecting hypertonic glucose into the knee joint while injecting 5% glucose around the sensory nerves around the knee joint
Sponsors
Li TieShan
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the standards established by the ACR and EULAR (Meeting (1), and meeting any 2 of (2), (3), (4), and (5) at the same time, KOA can be diagnosed): (1) Repeatedly within the past month Knee joint pain; (2) X-ray (standing position or weight-bearing position) shows joint space narrowing, subchondral bone sclerosis and/or cystic degeneration, joint edge osteophyte formation; (3) Aged >= 48 years; (4) Morning Stiff time = 5; 4. Patients with poor curative effect after conservative treatment and strong willingness to injection treatment.
Exclusion criteria
Exclusion criteria: Exclusion criteria (satisfy one): 1. The diseased joints are combined with infection (including skin ulceration and infection around the injection site), joint tumors or tuberculosis; 2. Abnormal blood coagulation; 3. Severe cardiopulmonary disease and severe liver and kidney insufficiency; 4. No Cooperative treatment and follow-up patients with cognitive or mental disorders; 5. History of intra-articular drug injection and knee surgery within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Western Ontario and McMaster Universities Arthritis Index;pressure pain threshold; | — |
Countries
China
Contacts
Public ContactLI Tieshan
The Affiliated Hospital of Qingdao University
Outcome results
None listed