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Renin-angiotensin system mechanism underlying the effect of auricular acupuncture on blood pressure in hypertensive patients with phlegm-dampness constitution: a randomized controlled trial

Renin-angiotensin system mechanism underlying the effect of auricular acupuncture on blood pressure in hypertensive patients with phlegm-dampness constitution: a randomized controlled trial

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062800
Enrollment
Unknown
Registered
2022-08-19
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Sponsors

School of Nursing, Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1. Individuals of both sexes, aged between 45 and 74 years; 2. diagnosed with PDC by tongue observation and the Classification and Determination of Constitution in TCM scale; 3. diagnosed with EH according to the diagnostic criteria of the International Society of Hypertension Global Hypertension Practice Guidelines

Exclusion criteria

Exclusion criteria: 1. Individuals with mixed TCM constitutions; 2. allergy to the medical devices involved in this trial; 3. poor medication compliance; 4. the presence of serious complications such as severe arrhythmia or end-stage renal disease; 5. ear infections, ulcers, swelling, or lack of skin integrity at the application sites during the course of the study; 6. pregnancy or lactation during the trial; 7. history of mental disease; 8. presence of malignant tumors; 9. taking ACE inhibitors or angiotensin receptor blockers; 10. has received any other antihypertensive clinical test.

Design outcomes

Primary

MeasureTime frame
blood pressure;

Secondary

MeasureTime frame
phlegm-dampness constitution;Protein expression products of RAS;Key genes of RAS;

Countries

China

Contacts

Public ContactCuizhen Shen

School of Nursing, Zhejiang Chinese Medical University

shencuizhen@163.com+86 15968805976

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026