COVID-19
Conditions
Interventions
Intervention group:Inhalation of Recombinant human interferon alpha2b aerosol
Control group:Inhalation of saline
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 18 years old at least. 2. Tested positive for SARS-CoV-2 and categorized as mild,moderate or non-symptomatic SARS-CoV-2 infector according to the Ver.9 guild book for COVID-19. 3. Subject must committed to take specified contraception. 4. Subject must sufficiently understand the research progress. 5. ICF which approved by ethic committee must be signed. 6. Subject must commit to obey the requirement from researchers.
Exclusion criteria
Exclusion criteria: 1. Subject has much probability to proceed to severe or critical COVID-19. 2. Conducting or about to conduct mechanical ventilation. 3. With infection other than COVID-19. 4. HIV infector. 5. ALT/AST>1.5 ULN in screening period. 6. Allergy to any ingredient in investigation therapy. 7. Subject with any medical condition that unsuitable for this trial. 8. Subject accepted therapy that probably interfere the evaluation of investigation therapy. 9. Subject accepted plasma therapy. 10. Subject has been enrolled in clinical trials in 30 days. 11. Subject isn't thought compatible with currently on-going clinical trials. 12. Female subject in pregnancy of breast-feeding period or having plan to have a baby. 13. Couple of male subject is planing to have a baby.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to turn negative for SARS-CoV-2 test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comprehensive safety; | — |
Countries
China
Contacts
Public ContactXiaohong Fan
Shanghai Public Health Clinical Center
Outcome results
None listed