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Effective dose of remazolam tosylate combined with subthreshold dose of esketamine for inhibiting cardiovascular response to endotracheal intubation in the elderly

Effective dose of remazolam tosylate combined with subthreshold dose of esketamine for inhibiting cardiovascular response to endotracheal intubation in the elderly

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062787
Enrollment
Unknown
Registered
2022-08-18
Start date
2022-08-15
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia induction medication

Interventions

test group:Remazolam tosylate combined with esketamine for induction of anesthesia

Sponsors

Dazhu County People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18~40 years old; 2. ASA I~II grade; 3. Full-term gestational age, 37 to 42 weeks; 4. Sign the informed consent form and cooperate with the completion of the test.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to all drugs and excipients during anesthesia and postoperative analgesia; 2. Serious obstetric complications or serious underlying diseases during pregnancy; 3. Suffering or ever suffering from mental illness; 4. Those who are dependent on drugs, alcohol, etc.; 5. Are or have been subjected to domestic violence; 6. The fetus has congenital diseases; 7. Circumstances that the investigator considers inappropriate to be included in the study.

Design outcomes

Primary

MeasureTime frame
Effective dose of remazolam tosylate for induction of anesthesia;

Countries

China

Contacts

Public ContactChunyan Zhao

Dazhu County People's Hospital

404654508@qq.com+86 13368296999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026