Skip to content

Efficacy observation of low-dose esketamine combined with butorphanol for depression and pain after cesarean section

Efficacy observation of low-dose esketamine combined with butorphanol for depression and pain after cesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062785
Enrollment
Unknown
Registered
2022-08-18
Start date
2022-08-15
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative depression and pain

Interventions

test group:Esketamine 0.5mg/kg + Butorphanol 10mg diluted to 100ml with 0.9% sodium chloride injection
control group:Butorphanol 10mg diluted to 100ml with 0.9% Sodium Chloride Injection

Sponsors

Dazhu County People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Age 18~40 years old; 2. ASA I~II grade; 3. Full-term gestational age, 37 to 42 weeks; 4. Sign the informed consent form and cooperate with the completion of the test.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to all drugs and excipients during anesthesia and postoperative analgesia; 2. Serious obstetric complications or serious underlying diseases during pregnancy; 3. Suffering or ever suffering from mental illness; 4. Those who are dependent on drugs, alcohol, etc.; 5. Are or have been subjected to domestic violence; 6. The fetus has congenital diseases; 7. Circumstances that the investigator considers inappropriate to be included in the study.

Design outcomes

Primary

MeasureTime frame
MBS score;

Secondary

MeasureTime frame
NRS score;

Countries

China

Contacts

Public ContactChunyan Zhao

Department of Anesthesiology, Dazhu County People's Hospital

404654508@qq.com+86 13368296999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026