post-stroke aphasia
Conditions
Interventions
Group 1:600 pulses cTBS
Group 2:1200 pulses cTBS
Group 3:1800 pulses cTBS
Sponsors
Beijing Boai Hospital, China Rehabilitation Research Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients met the diagnostic criteria of ischemic stroke or hemorrhagic stroke, and the course of disease was 1-6 months; 2. It meets the diagnostic criteria for aphasia, with an aphasia quotient of less than 93.8; 3. No obvious sequelae after first onset or previous onset; 4. 18-75 years old; 5. Before the onset of the disease, the language function is normal, and the mother tongue is Chinese, primary school education or above; 6. Patients and their family members understand the test and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Aphasia caused by brain tumor, Parkinson's disease, motor neurone disease and other neurological diseases other than stroke or brain trauma; 2. patients with cardiac pacemaker, cochlear implant or other metal foreign body and any electronic device implanted in the body, MRI scan contraindications such as claustrophobia, and TMS treatment contraindications; 3. a history of epilepsy (having at least two uninduced seizures more than 24 hours apart, or having seizures within the past 12 months); 4. Patients with serious systemic diseases of heart, lung, liver, kidney and other diseases that cannot be controlled by conventional medication after laboratory examination or examination; 5. patients with severe dysarthria, cognitive impairment, deafness, visual impairment and so on cannot cooperate with the test; 6. patients with severe depression or anxiety, or diagnosed with other mental diseases that make them unable to complete the test; 7. History of alcohol and drug abuse; 8. women who are pregnant or planning to become pregnant; 9. patients who had received TMS within the past 3 months; 10. Participants in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Aphasia Battery; | — |
Countries
China
Contacts
Public ContactJingdu Zhao
Beijing Boai Hospital, China Rehabilitation Research Center
Outcome results
None listed