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The aftereffects of contraceptive methods in women: a bidirectional cohort study

The aftereffects of contraceptive methods in women: a bidirectional cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062776
Enrollment
Unknown
Registered
2022-08-18
Start date
2022-08-15
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The aftereffects of contraceptive methods in women

Interventions

Silver clip sterilization group:none
The sterilization group receivingPomeroy sterilization, translation of core packing method, or simple ligation sterilization :none
Tool contraceptive group :none
Subcutaneous implant contraceptive group :none

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for the experimental group 1. Women with a history of silver clip sterilization who intend to have surgery for benign gynecological conditions, including bilateral fallopian tube removal; 2. After sterilization, the patient stays for a very long time in their place of origin; 3. The patients consent and can adhere to the scheduled study visits, treatment schedules, lab tests, and other study procedures. Inclusion criteria for the control group: 1. Women who have previously undergone the pomeroy sterilization, translation of core packing method, or simple ligation sterilization; women who have had contraceptive implants; women who have used contraceptives; or women who have had male sterilization. presently preparing for surgery to treat benign gynecological conditions (surgical resection includes removal of both fallopian tubes); 2. Age 40-70 years old; 3. The rest of the criteria were the same as the inclusion criteria of the experimental group.

Exclusion criteria

Exclusion criteria: Exclusion criteria of the experimental group: 1. those who have undergone procedures in the past with other metal sutures or clips; 2. those who have previously undergone other metal implants (such as esophageal pacemaker implantation, heart valve replacement, fracture metal material fixing, etc.); 3. those whose workplaces are contaminated with heavy metals; 4. those who reside 20 km or less from a factory contaminated with heavy metals; 5. those who have a history of utilizing silver utensils, long-term use of silver jewelry, hair dye, or makeup; 6. those who currently have or have in the past had a serious pelvic and abdominal infection; 7. People who, in the researchers' opinion, are unsuitable for participation in this study. Exclusion criteria for the control group: the same as the exclusion criteria for the experimental group

Design outcomes

Primary

MeasureTime frame
Silver ion concentration in body fluids;

Secondary

MeasureTime frame
Numbercal density, volume density and surface density of fallopian tube epithelial cell organelles and Scanning Electron Microscope Spectroscopic Analysis;Tumor necrosis factor-a, interleukin-1ß, interleukin-6, interleukin-8, interleukin-10 in body fluids;Pelvic Adhesion Score;Coagulation function;

Countries

China

Contacts

Public ContactLijuan Zhang

The Second Hospital of Hebei Medical University

lijuan35@sina.com+86 13503212131

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026