The aftereffects of contraceptive methods in women
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for the experimental group 1. Women with a history of silver clip sterilization who intend to have surgery for benign gynecological conditions, including bilateral fallopian tube removal; 2. After sterilization, the patient stays for a very long time in their place of origin; 3. The patients consent and can adhere to the scheduled study visits, treatment schedules, lab tests, and other study procedures. Inclusion criteria for the control group: 1. Women who have previously undergone the pomeroy sterilization, translation of core packing method, or simple ligation sterilization; women who have had contraceptive implants; women who have used contraceptives; or women who have had male sterilization. presently preparing for surgery to treat benign gynecological conditions (surgical resection includes removal of both fallopian tubes); 2. Age 40-70 years old; 3. The rest of the criteria were the same as the inclusion criteria of the experimental group.
Exclusion criteria
Exclusion criteria: Exclusion criteria of the experimental group: 1. those who have undergone procedures in the past with other metal sutures or clips; 2. those who have previously undergone other metal implants (such as esophageal pacemaker implantation, heart valve replacement, fracture metal material fixing, etc.); 3. those whose workplaces are contaminated with heavy metals; 4. those who reside 20 km or less from a factory contaminated with heavy metals; 5. those who have a history of utilizing silver utensils, long-term use of silver jewelry, hair dye, or makeup; 6. those who currently have or have in the past had a serious pelvic and abdominal infection; 7. People who, in the researchers' opinion, are unsuitable for participation in this study. Exclusion criteria for the control group: the same as the exclusion criteria for the experimental group
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Silver ion concentration in body fluids; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numbercal density, volume density and surface density of fallopian tube epithelial cell organelles and Scanning Electron Microscope Spectroscopic Analysis;Tumor necrosis factor-a, interleukin-1ß, interleukin-6, interleukin-8, interleukin-10 in body fluids;Pelvic Adhesion Score;Coagulation function; | — |
Countries
China
Contacts
The Second Hospital of Hebei Medical University