general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: FB patients under moderate sedation; Age 45 to 65 years old; American Society of anesthesiologists (ASA) class I-II; Operation time 90% when inhaling air into the room.
Exclusion criteria
Exclusion criteria: Known local anesthetic allergy history (RF, midazolam, propofol or cyclophosphamide); Previous lung diseases (such as chronic obstructive pulmonary disease (COPD), respiratory failure and asthma); Severe sleep apnea syndrome (apnea hypopnea index >40); Body mass index (BMI) >30 kg/m2; Communication barriers; Have a history of neuropsychiatric disorder, cerebrovascular disease or abnormal liver and kidney function; History of nasopharyngeal surgery; Second or third degree atrioventricular block; Bradycardia (heart rate (HR) < 60 beats / min); Tobacco and alcohol dependence; Participate in other clinical trials within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of operation completion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time index;Hemodynamics;Intubation conditions;Minimum oxygen saturation;Patient and bronchoscope doctor satisfaction;Repeated bronchoscopy willingness and adverse reactions; | — |
Countries
China