pediatric defecation disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 6-18 years old (female or male); 2. Screening patients with functional constipation according to Rome IV standard (1). It must include the following 2 or more items, and the symptoms shall be at least once a week for at least 1 month. 1) Defecate twice a week or less; 2) Fecal incontinence at least once a week; 3) Have a history of passive posture or excessive tolerance of fecal retention; 4) Have a history of pain in defecation or draining hard feces; 5) There is a large mass of feces in the rectum; 6) Have a history of discharging coarse feces, and even cause toilet blockage; 7) After moderate evaluation, the symptoms cannot be completely explained by other disease conditions. (2) Laxatives are rarely used. (3) It does not meet the diagnostic criteria of irritable bowel syndrome. 3. STC, DD, mixed constipation were confirmed by colon transit test (CTT) and defecography; 4. Agree to abide by all conditions of the study in good faith and participate in all necessary learning, training and evaluation; 5. Informed consent must be provided and signed prior to any study related procedures.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet any of the above inclusion conditions; 2. Patients with colorectal organic diseases, such as colorectal space occupying and inflammation, were excluded by barium enema, defecography, electronic colonoscopy and other imaging methods; 3. Other serious systemic chronic diseases, such as cardiopulmonary, liver and kidney insufficiency, hematological diseases, hypothyroidism or hyperthyroidism, and systemic connective tissue diseases, were excluded by asking medical history, physical examination and routine blood physiological examination; 4. People with abnormal mental functions such as depression, anxiety and irritability, as well as patients with hemiplegia, spinal cord injury, mental retardation and other uncooperative patients; 5. Previous abdominal and pelvic surgery; 6. Pregnant or lactating; 7. Patients with other anorectal diseases or symptoms, such as hemorrhoids, severe pain around the anus and other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| colon transit time;Anorectal manometry;Defecography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pelvic floor electromyography; | — |
Countries
China
Contacts
Tianjin Medical University General Hospital