Uterine cavity adhesions
Conditions
Interventions
Experimental group:After hysteroscopic adhesion, umbilical cord blood mononuclear cells are injected from the uterine muscle layer
Control group:Only hysteroscopic adhesion is performed
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for uterine adhesions, and the imaging diagnosis determines the intimal damage; 2. Clearly understand the purpose and nature of the treatment and sign an informed consent form; 3. Female patients >= 18 years old and <= 45 years old; 4. The patient has the ability to answer the questionnaire; 5. Uterine adhesions occur after hysterical surgery, and hysteroscopic hysteroscopic adhesions are required; 6. Have not received treatment for endometrial damage within 6 months before surgery.
Exclusion criteria
Exclusion criteria: 1. Physiological amenorrhea such as pregnancy or breastfeeding, or menorrhea and amenorrhea caused by hyperprolactinemia, polycystic ovary syndrome, premature ovarian failure, pituitary disease or thyroid disease; 2. Hysteroscopy confirms that there are other endometrial diseases (such as fibroids, tuberculosis, uterine malformations, endometriosis, etc.); 3. Patients with acute and subacute genital tract inflammation; 4. Patients with malignant tumors (including present symptoms and past history); 5. Combined with other diseases, such as breast diseases, thrombophilic tendencies, lung diseases, etc.; 6. Liver function ALT and AST exceed the upper limit of the reference value by 1.5 times, or renal function Scr exceeds the upper limit of the reference value; 7. Patients who have undergone uterine cavity adhesion isolation; 8. Those who have participated in clinical trials of other drugs in the past three months; 9. Patients with psychiatric or neurological diseases; 10. Other patients whose condition is unstable and the doctor deems it unsuitable to participate in the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness;Endometrial volume;Endometrial vascularization index;Endometrial blood flow index;Endometrial vascularized blood flow index; | — |
Countries
China
Contacts
Public ContactFei Wang
Shandong Provincial Hospital
Outcome results
None listed