Effect of two different ultrasound-guided quadratus lumborum block approaches on postoperative analgesia in patients undergoing laparoscopic radical resection of rectal cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062716

Enrollment

Unknown

Registered

2022-08-16

Start date

2022-08-15

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic radical resection of rectal cancer

Interventions

anterior quadratus lumborum block at the lateral supra-arcuate ligament group:before induction, anterior quadratus lumborum block at the lateral supra-arcuate ligament was performed with 0.375% ropi

posterior quadratus lumborum block group:before induction,posterior quadratus lumborum block was performed with 0.375% ropivacaine at both side

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18 years < age <80 years 2. Body mass index (BMI): 18-30 kg/m^2. 3. ASA: Class I-II. 4. Patients undergoing laparoscopic radical resection of rectal cancer (Dixon surgery). 5. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications of regional nerve block: abnormal coagulation function, puncture site infection, local anesthetic allergy, etc.; 2. Long-term use of opioids (daily use of opioids, equivalent to 30mg morphine for more than 6 months) and history of chronic pain; 3. Unable to cooperate with researchers for any reason: hearing impairment, language comprehension impairment;Do not understand the use of VAS; Refusing to participate in the study; 4. Patients with severe respiratory and circulatory diseases and abnormal liver and kidney functions; 5. Patients with a history of neurological and mental diseases, and long-term use of sedative drugs; 6. Patients with moderate or higher anemia (Hb<90g/L).

Design outcomes

Primary

Measure	Time frame
Opioid consumption within 48 hours after operation;	—

Secondary

Measure	Time frame
Quality recovery questionnaire within 24 hours after operation;The first time to press analgesic pump after operation;Ramsay score and VAS scores for resting and exercise at T1(2h)?T2(6h)?T3(12h)?T4(24h)?T5(48h)after extubation;The blocked dermatomal coverage 5 min?15 min?30 min after block operation.;Intraoperative opioid consumption.;Incidence of PONV and doses of antiemetics after surgery;Incidence and Doses of the rescue analgesic after surgery;time of first flatus and ambulation after operation;Patient satisfaction score;Other postoperative adverse reactions occurred;	—

Measure

Time frame

Quality recovery questionnaire within 24 hours after operation;The first time to press analgesic pump after operation;Ramsay score and VAS scores for resting and exercise at T1(2h)?T2(6h)?T3(12h)?T4(24h)?T5(48h)after extubation;The blocked dermatomal coverage 5 min?15 min?30 min after block operation.;Intraoperative opioid consumption.;Incidence of PONV and doses of antiemetics after surgery;Incidence and Doses of the rescue analgesic after surgery;time of first flatus and ambulation after operation;Patient satisfaction score;Other postoperative adverse reactions occurred;

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Countries

China

Contacts

Public ContactMengxing Jia

xzmu_jiamengxing@126.com+86 15895238016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026