schizophrenia
Conditions
Interventions
one:Cognitive training
Sponsors
Peking University Sixth Hospital, Peking University Institute of Mental Health
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Healthy control group: 1. Age between 18-40 years old; 2. Right-handedness; 3. Years of education >= 5 years. Schizophrenia group: 1. according to DSM-5 diagnostic criteria for schizophrenia; 2. Age between 18-40 years old; 3. had >= 5 years of education; 4. were largely stable, with medication type and dose stable for >1 month and no medication adjustment planned during the study, with PANSS scores: P1 (delusions), P2 (conceptual disorganization), P3 (hallucinatory behavior), P5 (exaggeration), P6 (suspicion/persecution ) and G9 (unusual thought content) scores were less than 5; 5. Right-handedness
Exclusion criteria
Exclusion criteria: Healthy control group: 1. first-degree relatives with previous mental disorders or hereditary neurological disorders; 2. eyes with nearsightedness > 800 degrees, color weakness, color blindness, or other visual disorders; 3. pregnant or lactating women; 4. the presence of contraindications to MRI. Schizophrenia group: 1. eye nearsightedness > 800 degrees, color weakness, color blindness or other visual impairment; 2. Persons who have suffered from organic brain disease, concomitant physical severe disease, or central nervous system disease; 3. Women during pregnancy or lactation; 4. had MECT or rTMS treatment in the last 6 months; 5. Currently taking a generation of antipsychotics or clozapine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eye movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| cognitive function;Function Connection; | — |
Countries
China
Contacts
Public ContactChuan Shi
Outcome results
None listed