digestion
Conditions
Interventions
group P:introvenous propofol 2mg/kg
group R:introvenous remimazolam 0.2mg/kg
Sponsors
Zhuji People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Aged 18-64 years, gender unlimited, ASA I-II, BMI 18-30 kg/m2.
Exclusion criteria
Exclusion criteria: 1. Known allergies to benzodiazepines or dairy products, has a history of bronchial asthma, myasthenia gravis patients, patients with schizophrenia and severe depression; 2. Pregnant and lactating women; 3. Patients with endoscopic check contraindicated; 4. Patients with difficult intubation have predictable, severe sleep apnea, obese patients, patients with severe bradycardia, patients with acute upper gastrointestinal bleeding; 5. Patients with preoperative history of hypertension, patients without history of hypertension but preoperation with SBP (systolic blood pressure) >= 160mmHg, DBP (diastolic blood pressure) >= 95mmHg, HR (heart rate) >= 110 beats/min or <= 50 beats/min.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| feasibility of performing colonoscopy;the effect of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| patients' body movement during colonoscopy;dose addition time points during colonoscopy;addition dosage;dose addition times;awaking time after colonoscopy;SpO2;blood pressure; | — |
Countries
China
Contacts
Public ContactZhao Gang
Zhuji People's Hospital
Outcome results
None listed