Effect of remimazolam tosilate and propofol on circulation and sedation of laryngeal mask intubation under general anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062666

Enrollment

Unknown

Registered

2022-08-15

Start date

2022-08-20

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia induction

Interventions

group P:inject Propofol 2.0mg/kg

group R:inject renimazolam 0.2mg/kg

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged 18-64 years, gender unlimited, ASA grade I-II, BMI 18-30 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Patients with known benzodiazepine or dairy allergy, a history of bronchial asthma, myasthenia gravis, schizophrenia, and severe depression, predictable intubation difficulties, a history of preoperative hypertension; 2. Preoperative indurating catheters; 3. Patients with SBP (systolic blood pressure) >= 160mmHg, DBP (diastolic blood pressure) >= 95mmHg, HR (heart rate) >= 110 beats/min or <= 50 beats/min.

Design outcomes

Primary

Measure	Time frame
Induction success rate of general anesthesia;MOAA/S score <=1 time;bispectral index;	—

Secondary

Measure	Time frame
systolic pressure;diastolic pressure;mean arterial pressure;SpO2;heart rate;	—

Countries

China

Contacts

Public ContactZhao Gang

Zhuji People's Hospital

zg991337@126.com+86 13735215515

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026