Urolithiasis
Conditions
Interventions
case series:NA
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
Male
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who were diagnosed with calculi by medical history, signs, and preoperative imaging, and who were in line with surgical indications and underwent calculus removal; 2. The patients signed the informed consent for the operation and agreed to conduct urine microbial testing and stone composition analysis.
Exclusion criteria
Exclusion criteria: 1. The patient is diagnosed with urinary calculi but has no indication for surgery; 2. Primary or secondary hypercalcemia, including: hyperparathyroidism, milk-alkali syndrome, sarcoidosis or sarcoid-like disease, vitamin D intoxication, hyperthyroidism, pheochromocytoma, increased cortisol , adrenal insufficiency, vitamin A poisoning, etc.; 3. Patients with urinary tract stones caused by other potential causes, such as renal tubular acidosis, gout and some hereditary diseases, such as primary cystinuria, hyperuricemia, etc.; 4. Patients with congenital anatomical abnormalities, such as bladder neck stenosis, cavernous kidney, ureterocele, renal cyst, neurogenic bladder and congenital giant ureter; 5. The following medication history within two years before admission: amphotericin, HIV infection drugs (such as indinavir), magnesium silicate and sulfonamides; acetazolamide, corticosteroids, etc. 6. Patients who refuse to undergo urine microbiological analysis and stone composition analysis; 7. Patients who did not take stones according to the surgical standards during the operation; 8. Patients with malignant tumors; 9. Or at the discretion of the investigator, there may be other lesions that reduce the likelihood of inclusion or complicate inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic and vital signs data: age, height, weight, ethnicity, marriage; blood pressure, heart rate;General clinical data: medical history, course of disease, treatment history, comorbid diseases, drug use and social life factors (smoking, drinking, exercise, diet), whether or not the first stone was diagnosed, whether there was repeated urinary tract infection, etc.;Perioperative data: whether antibiotics were used before surgery, whether antibiotic resistance was used before surgery, surgical method, perioperative conditions (including whether plasma transfusion, whether to upgrade antibiotics, whether to use vasopressors, maximum body temperature), blood test results;Diet Structure Survey Indicators;Psychological Questionnaire Indicators;Urine 16s rDNA microbiota test results;Stone composition analysis test results;Safety; | — |
Countries
China
Contacts
Public ContactXiaoqiang Liu
Tianjin Medical University General Hospital
Outcome results
None listed