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Role of Galectin-3 and NLRP3 on vascular remodeling in senile coronary heart disease through inflammatory factor

Role of Galectin-3 and NLRP3 on vascular remodeling in senile coronary heart disease through inflammatory factor

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062651
Enrollment
Unknown
Registered
2022-08-14
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

CHD:NA
not CHD:NA

Sponsors

Tianjin First Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: The elderly patients who were admitted to our department due to cardiovascular disease and signed the informed consent for this study for the purpose of examination or treatment, and received coronary angiography.

Exclusion criteria

Exclusion criteria: 1. Patients with acute myocardial infarction and acute heart failure who need to use vasoactive drugs to maintain hemodynamic stability; 2. Severe peripheral atherosclerotic lesions may affect the measurement of peripheral blood pressure; 3. Patients who have a history of mental illness or family history of mental illness and do not have full behavioral capacity; 4. History of cancer without cure or remission, and the life expectancy is less than 1 year; 5. Risk of blood system diseases and severe bleeding; 6. Moderate to severe renal insufficiency and high risk of contrast nephropathy; 7. Patients participating in other clinical trials; 8. The researchers of this research group think that other reasons are not suitable for clinical trials.

Design outcomes

Secondary

MeasureTime frame
Galectin-3;NLRP3;Gensini score;

Countries

China

Contacts

Public ContactLuo Di

Tianjin First Central Hospital

luodi12@126.com+86 13920659422

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026