The dose-response of phenylephrine with continuous infusion to prevent post-spina hypotension for obese parturients undergoing cesarean sectionin

ED50 and ED95 of phenylephrine with continuous infusion to prevent post-spina hypotension for obese parturients undergoing cesarean sectionin

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062650

Enrollment

Unknown

Registered

2022-08-14

Start date

2022-08-01

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotension

Interventions

group 0.05:0.05 µg/kg/min norepinephrine infusion

group 0.025:0.025 µg/kg/min norepinephrine infusion

group 0.0375:0.0375 µg/kg/min norepinephrine infusion

group 0.0625:0.0625 µg/kg/min norepinephrine infusion

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Body mass index >= 35 kg/m2; 2. Gestational age >= 37 weeks; 3. Those who voluntarily join the study and sign informed consent; 4. Selective cesarean section with cesarean section operation pointer.

Exclusion criteria

Exclusion criteria: 1. Major obstetric diseases (including severe gestational hypertension or severe preeclampsia); 2. Contraindications to spinal anesthesia; 3. The effect of spinal anesthesia is asymmetric.

Design outcomes

Primary

Measure	Time frame
blood presure;	—

Secondary

Measure	Time frame
side effects;	—

Countries

China

Contacts

Public ContactLiu Lin

Jiaxing Maternal and Child Health Hospital

13967358623@163.com+86 13967358623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026