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Study on the rationality of medication for stress ulcer prophylaxis in intensive care unit

A Pharmacist-based Intervention to Reduce Inappropriate Stress Ulcer Prophylaxis Use in an Intensive Care Unit in China: a pragmatic, multi-centre, cluster randomised, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062588
Enrollment
Unknown
Registered
2022-08-12
Start date
2022-08-10
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically illed patients

Interventions

intervention group:Usual care + standardized pharmacist intervention
control group:Usual care

Sponsors

West China Second University Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 200 Years

Inclusion criteria

Inclusion criteria: 1. ICU Inclusion criteria: ICU departments in the top-three general hospitals, with no restrictions on the type of ICU, and at least one clinical pharmacist. 2. Patients Inclusion criteria: Newly admitted patients over 18 years old.

Exclusion criteria

Exclusion criteria: Patients with indications for acid-suppressing drug therapy, including upper gastrointestinal bleeding, MALT lymphoma, gastroesophageal reflux disease (GERD), peptic ulcer, erosive esophagitis, gastrinoma (Zero-Ellison syndrome) , Eosinophilic esophagitis, Barrett's esophagitis, Helicobacter phylum infection.

Design outcomes

Primary

MeasureTime frame
SUP drug use rate during ICU hospitalization;Incidence of clinically significant bleeding during ICU hospitalization;—

Countries

China

Contacts

Public ContactZhang Lingli

West China Second University Hospital, Sichuan University

zhanglingli@scu.edu.cn+86 13908181418

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026