Hypotension
Conditions
Interventions
RE group:remimazolam tosilate plus ERAS
PE group:propofol plus ERAS
Sponsors
Guangdong Provincial Peoples Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) male or female aged =18 years old; (2) ASA-PS score of 1–3; (3) scheduled for an elective surgical procedure under GA, including general surgery, thoracic surgery and other sergeries (urological surgery, otolaryngology etc.); (4) scheduled for endotracheal insert removal and planning to return to the ward after surgery; and (5) confirmed ICF signature.
Exclusion criteria
Exclusion criteria: (1) patient or their legally authorized representative refuses to participate in the study; (2) disorder of consciousness due to severe neurological or mental system diseases or other causes; (3) inability to communicate due to low level of education or a language barrier; (4) alcohol or drug abuse or dependence; (5) allergy to benzodiazepine or contraindications; (6) enrolment in other clinical trials within the last 3 months; (7) participation in the trial is not considered appropriate by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the 24-hour postoperative quality of recovery-40 score;the rate of intraoperative hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| the 72-hour postoperative quality of recovery-40 score;the rate of sedative hypotension requiring treatment;anesthetic hemodynamic profiles;the incidence of delirium within 1 day;incidence of main cardiovascular-related adverse events within 30 days;lung events within 30 day;the rates of surgery-related complications within 30 day;the rate of acute kidney injury in hospital;the rate of emergency readmission within 30 day;the surgery-related mortality within 3 months;the quality of life within 3 months;the functional anesthetic capability; | — |
Countries
China
Contacts
Public ContactShu Haihua
Guangdong Provincial People's Hospital
Outcome results
None listed