Sufentanil-induced cough
Conditions
Interventions
experimental group:Esketamine 0.1mg/kg
control group:Saline
Sponsors
The 904th Hospital of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The age is between 18 and 65 years old; 2. ASA grade ? and ?; 3. BMI 18-30kg/m^2; 4. Patients to be operated on elective general anesthesia surgery; 5. Sign the informed consent form for anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients who refused to participate in this study 2. Previous smoking, asthma, chronic cough, and a history of upper respiratory tract infection within one month before the operation. 3. Patients with contraindications to melamine (such as glaucoma, macrovascular aneurysms, etc.) 4. Use drugs that may interfere with the study, such as angiotensin-converting enzyme inhibitors, antidepressants, bronchodilators, steroids, opioids, or other drugs. 5. Patients with severe abnormal heart, lung, liver, and kidney function 6. Have a history of mental illness or are unable to communicate and cooperate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| classification of cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart beats;Adverse reaction;Mean arterial pressure;pulse oxygen saturation; | — |
Countries
China
Contacts
Public ContactXingzhi Liao
The 904th Hospital of PLA
Outcome results
None listed