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The role of the sFlt-1/PlGF ratio in assessing pregnant women with fetal growth restriction: a prospective cohort study

The role of the sFlt-1/PlGF ratio in assessing pregnant women with fetal growth restriction: a prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062514
Enrollment
Unknown
Registered
2022-08-10
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fetal growth restriction

Interventions

High-risk group, low-risk group:sFlt-1/PlGF

Sponsors

Obstetrics and Gynecology Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Singleton pregnancy; 2. The diagnostic criteria for FGR must be met. (The fetal weight or abdominal circumference estimated by ultrasound is lower than the 10th percentile of the fetal weight or abdominal circumference for the same gestational age); 3. Agree to participate and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Twin or multiple pregnancies; 2. Fetal chromosomal abnormalities, major malformations, or congenital infections; 3. Severe mental disorder, unable to express wishes; 4. Conditions that require delivery as soon as possible (eclampsia, pulmonary edema, uncontrollable hypertension, severe visual impairment, severe headache, fetal death...); 5. There are obvious other abnormal signs, laboratory tests, and other clinical diseases, approved by the investigator's Judgment, not suitable to participate in the research; 6. According to the investigator's judgment, those who cannot be observed and followed up to obtain delivery information.

Design outcomes

Primary

MeasureTime frame
sFlt-1/PlGF;

Countries

China

Contacts

Public ContactXiong Yu
xiongyu1535@163.com+86 13524636298

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026