Acute Respiratory Distress Syndrome (ARDS)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The first stage is a retrospective study: 1. Aged >= 18 years; 2. Meet the diagnosis of ARDS (1) Acute onset or worsening of respiratory symptoms within one week; (2) Respiratory failure that cannot be explained by cardiac insufficiency or fluid overload; (3) Bilateral infiltrates that cannot be fully explained by pleural effusion, nodules, masses, or atelectasis; (4) PaO2/FiO2 5 cmH2O); The second stage is a prospective cohort study: 1. Aged >= 18 years; 2. Meet the diagnosis of ARDS (1) Acute onset or worsening of respiratory symptoms within one week; (2) Respiratory failure that cannot be explained by cardiac insufficiency or fluid overload; (3) Bilateral infiltrates that cannot be fully explained by pleural effusion, nodules, masses, or atelectasis; (4) PaO2/FiO2 5 cmH2O); 3. The attending physician plans to perform lung recruitment based on the patient's condition; 4. Informed consent from the patient or family members.
Exclusion criteria
Exclusion criteria: The first stage is a retrospective study: 1. Patients who have not undergone ultrasound examination; 2. Pregnant women The second stage is a prospective cohort study: 1. The patient has subcutaneous emphysema in the chest, and the heart cannot be detected by ultrasound; 2. Pregnant woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apical four-chamber view;parasternal left ventricular short axis view;Apical five-chamber view;Long and short axes of the inferior vena cava;Tidal Volume (Vt);Peak pressure (Ppeak);Static lung compliance (Cstat);Platform pressure (Pplat);Driving pressure (Pdp);Lung ultrasound score;heart rate;cardiac rhythm;blood pressure;oxygen saturation;Number of hemodynamic fluctuations;Incidence of acute right heart dysfunction;Incidence of new-onset organ dysfunction;Mechanical ventilation with machine time;ICU length of stay;ICU inpatient mortality rate; | — |
Countries
China
Contacts
West China Hospital of Sichuan University