Depression, Bipolar Depression
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients in unipolar depression Inclusion criteria (all 7 below are met) 1. Age 18-65 years old (including 18 years old and 65 years old), regardless of gender; 2. Meet the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) diagnostic criteria for recurrent depressive disorder (confirmed by MINI 7.0), without psychotic symptoms; 3. The course of the disease is less than or equal to 6 months; 4. HAMD-17 total score > 17 points at the time of enrollment; 5. No MECT treatment within 14 days before enrollment; 6. Able to understand the content of scales and phonetic paradigms; 7. The patient himself or his family members signed a written informed consent. Patients in Bipolar disorder, currently suffering from a depressive episode Inclusion Criteria (6 all met) 1. Age 18-65 (including 18 and 65), regardless of gender; 2. Meet the diagnostic criteria for bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5), currently a depressive episode (diagnosis of MINI 7.0), without psychotic symptoms; 3. HAMD-17 total score > 17 points, YMRS total score < 6 points at the time of enrollment; 4. No MECT treatment within 14 days before enrollment; 5. Be able to understand the content of scales and phonetic paradigms; 6. The patient himself or his family members signed the written informed consent.
Exclusion criteria
Exclusion criteria: Patients in unipolar depression Exclusion Criteria (1 to exclude) 1. A diagnosis of mental disorder that meets the DSM-5 diagnostic criteria for mental retardation, schizophrenia spectrum disorder, bipolar disorder, and somatic symptoms and related disorders; 2. Visual impairment, currently suffering from oral and throat diseases and other serious physical diseases; 3. Positive family history of bipolar disorder, schizophrenia, and schizoaffective disorder; 4. History of alcohol or psychoactive substance abuse or dependence within 1 year; 5) The mental symptoms are too severe and it is difficult to cooperate with the completion of the research content. Patients with bipolar disorder, currently suffering from a depressive episode Exclusion Criteria (Exclude if 1 is met) 1. A diagnosis of mental disorder that meets the DSM-5 diagnostic criteria for mental retardation, schizophrenia spectrum disorder, and somatic symptoms and related disorders; 2. Visual impairment, currently suffering from oral and throat diseases and other serious physical diseases; 3. History of alcohol or psychoactive substance abuse or dependence within 1 year; 4. The mental symptoms are too severe and it is difficult to cooperate with the completion of the research content.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference Values in Word Usages;Difference Values in Acoustic Characteristics;Precision of Semantic Analysis Model;Recall of Semantic Analysis Model;F1 Value of Semantic Analysis Model;Precision of Acoustic and Semantic Multi-model;Recall of of Acoustic and Semantic Multi-model;F1 Value of of Acoustic and Semantic Multi-model; | — |
Countries
China