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A study on the use of voice information in the differential diagnosis of unipolar and bipolar depressive episodes

A study on the use of voice information in the differential diagnosis of unipolar and bipolar depressive episodes

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062502
Enrollment
Unknown
Registered
2022-08-09
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Bipolar Depression

Interventions

Sponsors

Beijing Anding Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients in unipolar depression Inclusion criteria (all 7 below are met) 1. Age 18-65 years old (including 18 years old and 65 years old), regardless of gender; 2. Meet the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) diagnostic criteria for recurrent depressive disorder (confirmed by MINI 7.0), without psychotic symptoms; 3. The course of the disease is less than or equal to 6 months; 4. HAMD-17 total score > 17 points at the time of enrollment; 5. No MECT treatment within 14 days before enrollment; 6. Able to understand the content of scales and phonetic paradigms; 7. The patient himself or his family members signed a written informed consent. Patients in Bipolar disorder, currently suffering from a depressive episode Inclusion Criteria (6 all met) 1. Age 18-65 (including 18 and 65), regardless of gender; 2. Meet the diagnostic criteria for bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5), currently a depressive episode (diagnosis of MINI 7.0), without psychotic symptoms; 3. HAMD-17 total score > 17 points, YMRS total score < 6 points at the time of enrollment; 4. No MECT treatment within 14 days before enrollment; 5. Be able to understand the content of scales and phonetic paradigms; 6. The patient himself or his family members signed the written informed consent.

Exclusion criteria

Exclusion criteria: Patients in unipolar depression Exclusion Criteria (1 to exclude) 1. A diagnosis of mental disorder that meets the DSM-5 diagnostic criteria for mental retardation, schizophrenia spectrum disorder, bipolar disorder, and somatic symptoms and related disorders; 2. Visual impairment, currently suffering from oral and throat diseases and other serious physical diseases; 3. Positive family history of bipolar disorder, schizophrenia, and schizoaffective disorder; 4. History of alcohol or psychoactive substance abuse or dependence within 1 year; 5) The mental symptoms are too severe and it is difficult to cooperate with the completion of the research content. Patients with bipolar disorder, currently suffering from a depressive episode Exclusion Criteria (Exclude if 1 is met) 1. A diagnosis of mental disorder that meets the DSM-5 diagnostic criteria for mental retardation, schizophrenia spectrum disorder, and somatic symptoms and related disorders; 2. Visual impairment, currently suffering from oral and throat diseases and other serious physical diseases; 3. History of alcohol or psychoactive substance abuse or dependence within 1 year; 4. The mental symptoms are too severe and it is difficult to cooperate with the completion of the research content.

Design outcomes

Primary

MeasureTime frame
Difference Values in Word Usages;Difference Values in Acoustic Characteristics;Precision of Semantic Analysis Model;Recall of Semantic Analysis Model;F1 Value of Semantic Analysis Model;Precision of Acoustic and Semantic Multi-model;Recall of of Acoustic and Semantic Multi-model;F1 Value of of Acoustic and Semantic Multi-model;

Countries

China

Contacts

Public ContactFeng Lei
flxlm@126.com+86 15810910218

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026