Postoperative pain
Conditions
Interventions
Intraoperative application of high dose remifentanil group:High dose remifentanil
Intraoperative application of low dose remifentanil group:Low dose remifentanil
Non remifentanil group:Normal saline
Sponsors
The First Affiliated Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with lower abdominal or gynecological surgery were ASA physical status I-II; 2. Aged 20-80 years; 3. Under general anesthesia after tracheal intubation; 4. The types of surgery included laparoscopic abdominal surgery.
Exclusion criteria
Exclusion criteria: 1. Allergic to any drug used for anesthesia; 2. Pregnancy or lactation; 3. Emergency operation; 4. Patients with long-term use of benzodiazepines or opioids; 5. Patients with chronic pain; 6. Patients with heart, kidney and liver failure; 7. Patients unable to perform pain assessment methods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain score;Hyperalgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Nausea and Vomiting, PONV;Shivering;Pruritus;Cough;Headache;Genetics of pain; | — |
Countries
China
Contacts
Public ContactJiehao Sun
The First Affiliated Hospital, Wenzhou Medical University
Outcome results
None listed