Postoperative delirium
Conditions
Interventions
Test group:Anesthesia induction with Esketamine
Control group:Anesthesia induced the same amount of normal saline.
Sponsors
Guangdong Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Elderly patients over 65 years old; 2. Scheduled pneumonectomy; 3. Sign the informed consent of the study; 4. ASA anesthesia grade I - III patients.
Exclusion criteria
Exclusion criteria: 1. The patient has mental diseases or other diseases that cannot be evaluated for delirium; 2. The patient has contraindications to the use of esketamine such as poorly controlled or untreated hypertension and increased intracranial pressure; 3. Have a history of allergy to ketamine or similar drugs; 4. Emergency surgery; 5. Those who participated in other clinical studies or refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum CRP; | — |
Countries
China
Contacts
Public ContactWang Sheng
Guangdong Provincial People's Hospital
Outcome results
None listed