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Improvement of postoperative ureterogenic bladder discomfort (CRBD) in male urology patients under butorphanol multimode general anesthesia

Improvement of postoperative ureterogenic bladder discomfort (CRBD) in male urology patients under butorphanol multimode general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062457
Enrollment
Unknown
Registered
2022-08-08
Start date
2022-08-08
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheter-related-bladder discomfort

Interventions

Butorphanol:Dexmedetomidine 2ug/kg.h Loading dose for 10min, methylprednone 40mg, flurbiprofen ester 50mg, propofol 2mg /kg, rocuronium 0.6mg/kg, butorphenol 30ug/kg
Fentanyl:Midazolam 0.05mg/kg, propofol 2 mg/kg, fentanyl 5ug/kg, rocuronium 1mg/kg

Sponsors

The Affiliated Hospital of Medical School, Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Male surgical patients with prolonged indwelling catheterization after urology surgery; 2. All were adult males; 3. Weight 48-85 kg; 4. ASA grade I - III; 5. Patients undergoing surgery with an estimated operation time of 1-4 hours.

Exclusion criteria

Exclusion criteria: 1. Long-term use of opioids, opioid tolerance; 2. Bladder outflow tract obstruction, neurogenic bladder, or overactive bladder (urinary frequency more than 3 times/night, or more than 8 times/24 h); 3. II - III degree atrioventricular block, sinus tachycardia, sinus bradycardia arrhythmia; 4. Myocardial infarction, perfusion artery dysfunction, heart failure; 5. Serious losers; 6. Parkinson's disease, patients taking stimulant CNS drugs or having CNS diseases, and psychiatric disorders; 7. Abnormal liver function (Child-Pugh score > 7); 8. End-stage renal disease; 9. Morbidly obese people; 10. Dependence on nacotin.

Design outcomes

Primary

MeasureTime frame
CRBD (Catheter-related-bladder discomfort) score;

Secondary

MeasureTime frame
Postoperative VAS analgesia score;Ramsay sedation score;

Countries

China

Contacts

Public ContactZhipeng Xu

The Affiliated Hospital of Medical School, Ningbo University

xuzhipeng20@163.com+86 15210319808

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026