Postoperative delirium
Conditions
Interventions
Remimazolam group:Remimazolam
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients undergoing hip arthroplasty under general anesthesia with laryngeal mask airway; 2. Patients with American Society of Anesthesiologists (ASA) physical status I-II; 3. Patients aged 65 or older; 4. Patients who agree to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients without good cognitive function(MMSE score 23 or less) and language skills or with a history of neurological, psychiatric or epileptic diseases before surgery; 2. Patients with serious cardiovascular and cerebrovascular diseases, uncontrolled diabetes, and liver and kidney dysfunction; 3. Patients allergic to study drugs; 4. Patients who have received analgesic drugs or have a history of treatment; 5. Patients who refused to receive PCIA pump treatment after surgery; 6. Patients participating in other clinical trials; 7. Patients with difficult postoperative follow-up or poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3D-Confusion Assessment Method (CAM), Chinese Version; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scale, VAS;Awakening time;Incidence of postoperative nausea and vomiting;Mini-mental State Examination, MMSE;Use of vasoactive drugs;Hemoglobin; | — |
Countries
China
Contacts
Public ContactDong-Liang Li
Qilu Hospital of Shandong University
Outcome results
None listed